Profile: Kary Mullis - Updated 2022 - Everyone Has V-AIDS!

With PCR, if you do it well, you can find almost anything in any- body-it starts making you believe in the, sort of, buddhist notion that everything is contained in everything else.

I mean, if you amplify one single molecule up to something you can really mea- sure-which PCR can do-then there's just very few molecules that you don't have at least one single one of in your body...

It allows you to take a very minuscule amount of anything and make it measurable and then talk about in meetings and stuff like it is important. See, that's not a misuse that's just sort of a misinterpretation...

Those tests are all based on things that are invisible, and the results are inferred, in a sense. PCR is separate from that, it's just a process that's used to make a whole lot of something out of something. It doesn't tell you that you're sick and it doesn't tell you that the thing you ended up with was really going to hurt you or anything like that.

Kary Mullis

Inventor of PCR and Nobel Prize laureate (1944-2019)

Note: generating not amplifying

Beginning with a single molecule of the genetic material DNA, the PCR can generate 100 billion similar molecules in an afternoon.

The reaction is easy to execute: it requires no more than a testtube, a few simple reagents and a source of heat.

The DNA sample that one wishes to copy can be pure, or it can be a minute part of an extremely complex mixture of biological materials.

The DNA may come from a hospital tissue specimen, from a single human hair, from a drop of dried blood at the scene of a crime, from the tissues of a mummified brain or from a 40,000-year-old woolly mammoth frozen in a glacier.

Kary B. Mullis: The Unusual Origin of the Polymerase Chain Reaction (Scientific American April 1990)

Jurassic Park was a PG horror action movie...right?

DNA replication...

"...the science of PCR, because it allows for the unlimited replication of small bits of DNA, was one of the inspirations of "Jurassic Park," the Michael Crichton novel about a theme park of cloned dinosaurs that Steven Spielberg turned into a movie franchise."

source: NY Times Obituary

waybacked

PCR explained

PCR and the importance of cycles

The hereditary substance DNA is present in the cell nuclei of animals, plants and fungi as a spirally twisted double strand. This double helix, whose discovery was also awarded a Nobel Prize, can be seen schematically in the illustration.2 It is the material basis of genes and contains all the information about an organism. DNA is the abbreviationofdeoxyribonucleicacid which is "nuclearacid"(from Latin nucleus) with the sugar deoxyribose.

The decisive factor here is the arrangement of four building blocks, the nucleotides (in the illustration with blue part horizontally be- tween the two backbone strands). They are lined up next to each other on the backbone strand and each nucleotide connects with another nucleotide on the opposite strand. The only possible con- nection is: adenine with thymine, guanine with cytosine.

These nucleotides abbreviated with A, T, G, C are organised in sections-the genes-and specify which proteins are finally formed from them: for example, enzymes for metabolism, antibodies for the immune response, structural proteins such as collagen for connective tissue or hair. By the way, you are synthesizing various proteins as you are reading this text.

(When PCR is used to search SARS-CoV-2, an additional prepara- tory step is required. The genetic material of the virus does not consist of DNA, but of a similar substance, RNA = ribonucleic acid. However, since the polymerase only works with DNA, the viral RNA must first be ""transcribed"" into DNA, then PCR can start).

For cell reproduction by division-your cells are also dividing just as you are reading-the DNA double strand opens and is duplicated by the enzyme polymerase which attaches the corresponding coun- terparts to the nucleotides of each strand: C to G, G to C, A to T, T to A. This creates two identical double strands, one of which migrates into each of the two newly formed cells.

The polymerase also duplicates the DNA when PCR is carried out; it enables the polymerase chain reaction, which takes place in cycles (C). In this process, the double-stranded DNA is first separated into two single strands by heating it to over 90. If the polymerase and the four nucleotides are then present in sufficient quantities as building material, the base pairs C-G and A-T join when the temperature is lowered to below 60℃, resulting in the duplication of the starting material.

However, since it is not possible to amplify a whole gene with PCR, but only a section of a gene, one chooses a section of interest within the gene. In order to let the polymerase start at exactly this section, one defines the starting point by setting the ""primer"" and carries out the reaction in a device called thermocycler: Heating, cooling, heating, cooling ... The resulting DNA is not seen directly, but via a fluorescent dye whose intensity is measured."

Thomas Kubo - The PCR disaster

Does this hero worship of Dr Kary Mullis really need to stop?

endless quotes of "The Great man"

In this Youtube Video TED Talk he talks of a breakthrough treatment he discovered and how injecting mice with anthrax and "curing" them didn't stop them dying...and having a good old laugh about it...

of course we all know that animals are useful in testing...so - Has his revolutionary treatment led to the death of the use of anti-biotics?

no.

Drug-resistant bacteria kills, even in top hospitals. But now tough infections like staph and anthrax may be in for a surprise. Nobel-winning chemist Kary Mullis, who watched a friend die when powerful antibiotics failed, unveils a radical new cure that shows extraordinary promise.

it's only science...

and he's a lovable old hippy...

really?

300 million bucks gone? lost to BIG PHARMA...

bitter much? wew!

PCR "was used as well to decode and map the entire human DNA as part of the Human Genome Project"....

"For his discovery, Cetus awarded Dr. Mullis $10,000, but the company later sold the rights to his PCR process to the pharmaceutical giant F. Hoffmann-La Roche for $300 million.

Dr. Mullis, believing he had been denied a just reward, remained bitter about it for the rest of his life." source:

NY Times Obituary

waybacked

The Human Genome Project (HGP) was one of the great feats of exploration in history. Rather than an outward exploration of the planet or the cosmos, the HGP was an inward voyage of discovery led by an international team of researchers looking to sequence and map all of the genes -- together known as the genome -- of members of our species, Homo sapiens.

Beginning on October 1, 1990 and completed in April 2003, the HGP gave us the ability, for the first time,

to read nature's complete genetic blueprint for building a human being.

https://www.genome.gov/human-genome-project

IBM links to The Human Genome Project

The DNA transistor

While the cost of sequencing DNA has dropped dramatically over the past decade, it's still expensive-about US$10,000 per individual. Scientists say the cost will have to drop to near US$100 before the full potential of the advances in genomic research can be realized.

That's where IBM Research comes in. By combining genetics with semiconductor technologies, at the Watson Research Lab in New York in 2007, scientists Gustavo Stolovitzky and Stanislav Polonsky invented a mechanism, which they called the IBM ® DNA Transistor, designed to make it possible to sequence genetic material accurately and cheaply-eventually, they hope, for a few hundred US dollars per person.

Their project is among a handful of promising initiatives that could bust open the field of genetics in the relatively near future. "How low can we go in price?" asks George Church, [note George Church links to Epstein] a professor of genetics at Harvard Medical School. "There are all sorts of applications where computing and sample preparation aren't limiting and the price can keep going down."

Here's how the DNA Transistor works: A silicon membrane is placed vertically in a solution-filled chamber, dividing it in two. Strands of genetic material are placed in one side of the chamber, and electrical charges are applied-negative in the part of the chamber where the genetic strands reside, and positive on the other side. The positive charge draws a strand of genetic material into a tiny opening, or nanopore, in the membrane. As the strand passes through the opening, the combination of the electrical charges and the composition of the membrane have the effect of ratcheting the strand through one bead of genetic material at a time. This mechanism makes it possible to accurately and quickly read the genetic makeup of the strand.

IBM

The Mapping of Humanity's Family Tree

also this

"The project took a major step forward in July 2010, when IBM and Swiss pharmaceutical giant Roche announced a joint effort to develop a commercial gene sequencer based on the DNA Transistor."

THATS THE SAME COMPANY THAT MADE $300 MILLION OUT OF MULLIS' PCR TEST & left him with $10,000

cure for major infections? No more need for Anti Biotics?

Cancer cured?

Back to that Youtube Video TED Talk where Kary Mullis talks of a breakthrough treatment he had discovered... and how mice with anthrax had become "cured"

does this not sound like Mr Mullis idea?

University of Edinburgh scientists successfully test cancer-killing 'Trojan Horse' drug

Researchers have successfully tested a "Trojan Horse" drug which can kill cancer and bacterial cells without damaging nearby healthy tissue. Scientists at the University of Edinburgh combined the tiny cancer-killing molecule SeNBD with a chemical food compound to trick malignant cells into ingesting it.

The peer-reviewed experimental study was carried out on zebrafish and human cells, but researchers say more studies are needed to confirm if it is a safe and swift method of treating early stage cancer and drug-resistant bacteria.

Herald Scotland

Cancer & Aging...Linked?

Cancer = cellular mutation... & Aging? based on same research

The Definition of Cancer

Cancer is a disease in which some of the body’s cells grow uncontrollably and spread to other parts of the body.

Cancer can start almost anywhere in the human body, which is made up of trillions of cells. Normally, human cells grow and multiply (through a process called cell division) to form new cells as the body needs them. When cells grow old or become damaged, they die, and new cells take their place.

Sometimes this orderly process breaks down, and abnormal or damaged cells grow and multiply when they shouldn’t. These cells may form tumors, which are lumps of tissue. Tumors can be cancerous or not cancerous (benign).

Cancerous tumors spread into, or invade, nearby tissues and can travel to distant places in the body to form new tumors (a process called metastasis). Cancerous tumors may also be called malignant tumors. Many cancers form solid tumors, but cancers of the blood, such as leukemias, generally do not.

Benign tumors do not spread into, or invade, nearby tissues. When removed, benign tumors usually don’t grow back, whereas cancerous tumors sometimes do. Benign tumors can sometimes be quite large, however. Some can cause serious symptoms or be life threatening, such as benign tumors in the brain. source

Aging = Damaged DNA leading to cellular mutation?

DNA damage theory of aging

From Wikipedia, the free encyclopedia

The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA damages. Damage in this context is a DNA alteration that has an abnormal structure. Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis. Nuclear DNA damage can contribute to aging either indirectly (by increasing apoptosis or cellular senescence) or directly (by increasing cell dysfunction).[1][2][3][4]

Several review articles have shown that deficient DNA repair, allowing greater accumulation of DNA damages, causes premature aging; and that increased DNA repair facilitates greater longevity. Mouse models of nucleotide-excision–repair syndromes reveal a striking correlation between the degree to which specific DNA repair pathways are compromised and the severity of accelerated aging, strongly suggesting a causal relationship.[5] Human populations studies show that single-nucleotide polymorphisms in DNA repair genes, causing up-regulation of their expression, correlate with increases in longevity.[6] Lombard et al. compiled a lengthy list of mouse mutational models with pathologic features of premature aging, all caused by different DNA repair defects.[7] Freitas and de Magalhães presented a comprehensive review and appraisal of the DNA damage theory of aging, including a detailed analysis of many forms of evidence linking DNA damage to aging.[2] As an example, they described a study showing that centenarians of 100 to 107 years of age had higher levels of two DNA repair enzymes, PARP1 and Ku70, than general-population old individuals of 69 to 75 years of age.[8][2] Their analysis supported the hypothesis that improved DNA repair leads to longer life span. Overall, they concluded that while the complexity of responses to DNA damage remains only partly understood, the idea that DNA damage accumulation with age is the primary cause of aging remains an intuitive and powerful one.[2]

In humans and other mammals, DNA damage occurs frequently and DNA repair processes have evolved to compensate.[citation needed] In estimates made for mice, DNA lesions occur on average 25 to 115 times per minute in each cell, or about 36,000 to 160,000 per cell per day.[9] Some DNA damage may remain in any cell despite the action of repair processes. The accumulation of unrepaired DNA damage is more prevalent in certain types of cells, particularly in non-replicating or slowly replicating cells, such as cells in the brain, skeletal and cardiac muscle.[citation needed]

"building genetic blueprint for building a human being"

life extension Israel?

Israeli scientists have found a way to increase the life expectancy of mice by 23 percent, in groundbreaking research that they hope to replicate in humans - who could then reach an average age of 120 years old.

The researchers boosted the life expectancy of 250 rodents by increasing the supply of SIRT6, a protein that normally wanes in the aging process, the Times of Israel reported.

NY Post

They increased the supply of a protein, SIRT6, which normally wanes with aging, in 250 mice. In peer-reviewed research just published in the journal Nature Communications, they have revealed the increased life expectancy - and also stated that the protein-rich mice were more youthful and less susceptible to cancer. Times of israel

Murdered HERO?

Fact checked? CONVINCED?

Scientist says HIV not cause of AIDS

By Kimberly Bufkin, Forty-Niner Online
April 17, 1995

Nobel Prize winner and future O.J. Simpson trial DNA expert witness Kary B. Mullis spoke on campus April 6 in the Small Auditorium of the University Student Union on his hypothesis that HIV is not the cause AIDS.

This was the second consecutive day that Mullis spoke on campus. On April 5, he discussed the differences and similarities between law and science.

Although he did not clearly define it during his presentation, Mullis' hypothesis is that AIDS is not caused by HIV, but by several retroviruses.

Mullis said that if a person's immune system was infected by a large collection of dormant retroviruses and if that group of cells divide and multiply, the dormant retrovirus will be copied.

When a retrovirus is copied, possibly into a million copies, it breaks loose from the cells and leaks into the blood stream. From then on a chain reaction is created, Mullis said.

"Eventually there is going to come a time when a percentage of the population is going to have AIDS and not have had HIV," Mullis said.

Mullis said he does not believe that HIV alone is not the cause of AIDS because he has yet to see any papers or proof that actually link HIV and AIDS. He suggested that anyone who has any papers to support the hypotheses that HIV is linked to AIDS, to send him a copy.

A student in the audience asked Mullis if he was telling them to be skeptical of HIV being the cause of AIDS, why shouldn't people be skeptical of all retroviruses, including HIV.

Mullis' response was that the cause of AIDS might not even be a virus, and that he was examining it in a different way than it has been now.

Should Mullis' suggested hypothesis prove to be true, vaccine for AIDS would be impossible to develop. Because there would be so many viruses, that once a person tried to knock out one, another would take its place, he said.

Mullis also said there is a high rate of false positive-AIDS tests and that many people are dying from AZT, one of the most commonly used drugs for HIV and AIDS patients.

"The established AIDS research committee is incapable of realizing that they may be wrong," Mullis said.

Mullis also responded to questions asked of him about the O.J. Simpson trial, where he will be on the stand as a defense witness in a couple of months, and about the autobiography that he is currently writing.

Both speeches were sponsored by the College of Natural Science and Mathematics.

source

AIDS, Opium, Diamonds & Empire - Dr. Banks

Part 1 - Part 2 - Part 3

1971 Research Logic Flow Chart of the formerly secret U.S. Special Virus Cancer Program (1962-1978).

The 1971 Research Logic Flow Chart was originally discovered and presented in 1999 by Dr. Boyd Ed Graves on Pg. 60-61 inside the 1971 and 1972 annual progress reports of the US Special Virus Cancer Program. The 1971 Flow Chart coordinates every contract, experiment, institution and every scientist who was involved in the covert federal virus development program.

This video asks the tough questions:
[WHO MADE IT? - if it's you - all credit and rights reserved]

Acquired immunodeficiency syndrome (AIDS)

is a chronic, potentially life-threatening condition caused by the human immunodeficiency virus (HIV). By damaging your immune system, HIV interferes with your body's ability to fight infection and disease.HIV is a sexually transmitted infection (STI). It can also be spread by contact with infected blood or from mother to child during pregnancy, childbirth or breast-feeding. Without medication, it may take years before HIV weakens your immune system to the point that you have AIDS. There's no cure for HIV/AIDS, but medications can dramatically slow the progression of the disease. These drugs have reduced AIDS deaths in many developed nations.

MAYO clinic

Severe Acute Respitory syndrome (SARS)

A new and rapidly progressive respiratory syndrome termed severe acute respiratory syndrome (SARS) was identified by the World Health Organization (WHO) in the Guangdong province of China as a global threat in March of 2003.

SARS went on to spread globally over the following months to over 30 countries and became the first pandemic of the 21st century. This activity reviews the evaluation and management of severe acute respiratory syndrome (SARS) and highlights the role of the interprofessional team in evaluating and managing patients suspected of or with SARS.

statpearls

HIV vaccine?

Four decades on, where's the HIV vaccine?

Issam AHMED - Mon, June 7, 2021, 4:15 AM·4 min read

In the four decades since the first cases of what would come to be known as AIDS were documented, scientists have made huge strides in HIV treatment, transforming what was once a death sentence to a manageable condition.

What we still don't have is a vaccine that would train human immune systems to ward off the infection before it ever takes root.

Here's the state of play on some of these efforts, which experts see as the "holy grail" in the fight to eliminate a virus that 38 million people live with globally.

- Why do we need a vaccine? -

More people than ever now have access to medications called antiretroviral therapy or ART, which when taken as prescribed, keeps down the amount of virus in their body.

This keeps them healthy and unable to transmit HIV to their partners.

Beyond ART, people at high risk for infection can now get pre-exposure prophylaxis, or PrEP, a pill taken every day that reduces the risk of infection by 99 percent.

"But access to medication is not organized in every part of the world," Hanneke Schuitemaker, global head of viral vaccine discovery at Johnson & Johnson's Janssen Vaccines, told AFP.

Even within wealthy countries, wide socio-economic and racial disparities exist in accessing these medicines, and vaccines have historically been the most effective tools to eradicate infectious diseases.

J&J is currently carrying out two human efficacy trials for its HIV vaccine candidate, and initial results from one of them may come as early as "the end of this year," Schuitemaker said.

- Why is it so challenging? -

Vaccines against Covid-19 were developed in record time and have shown remarkable levels of safety and efficacy, helping drive down caseloads in the countries fortunate enough to have wide access.

Many of these shots were developed using technologies that were previously being tried out on HIV -- so why haven't we had breakthroughs yet?

"The human immune system doesn't self cure HIV, whereas what was very clear was the human immune system was quite capable of self curing Covid-19," Larry Corey, principal investigator of HVTN, a global organization funding HIV vaccine development, told AFP.

Covid vaccines work by eliciting antibodies that bind to the virus' spike protein and stop it from infecting human cells.

HIV also has spike-shaped proteins on its surface, which are the target of HIV vaccine development.

But while Covid has tens of well known variants circulating worldwide, HIV has hundreds or thousands of variants inside each infected person, William Schief, an immunologist leading development of an mRNA HIV vaccine at Scripps Research Institute told AFP.

Because it's a "retrovirus" it quickly incorporates itself into its host's DNA. An effective vaccine will need to stop the infection dead in its tracks, not just reduce the amount of virus and leave the remainder to stay with the person forever.

- Where do things stand now? -

Efforts to develop a vaccine have been going on for decades but have so far all ended in failure.

Last year, a study called Uhambo that was taking place in South Africa and involved the only vaccine candidate ever shown to provide some protection against the virus frustratingly ended in failure.

J&J's vaccine candidate is currently being trialed in 2,600 women in sub-Saharan Africa in the Imbokodo trial, which is expected to report results in the coming months.

It's also being tested in around 3,800 men who have sex with men and transgender individuals across the US, South America and Europe in the Mosaico trial.

The J&J vaccine uses similar adenovirus technology to its Covid-19 vaccine, in other words a genetically modified cold virus delivers genetic cargo carrying instructions for the host to develop "mosaic immunogens" -- molecules capable of inducing an immune response to a wide variety of HIV strains.

This is followed up by directly injecting synthetic proteins in later doses.

Another promising approach is to try to generate "broadly neutralizing antibodies" (bnAbs) which bind to areas of the HIV virus that are common across its many variants.

The International AIDS Vaccine Initiative and Scripps Research recently announced results from an early stage trial showing their mRNA vaccine candidate, developed with Moderna, stimulated the production of rare immune cells that create bnAbs.

Their strategy, explained Schief, is to use a sequence of shots to try to gradually educate antibody producing B-cells. They also hope to train up another kind of white cell, known as T-cells, to kill any cells that still get infected despite the antibodies.

Efficacy trials are still a long way off, but he's hopeful the mRNA technology, which turn the body's cells into vaccine factories and has proven its worth against Covid-19, can make the difference.

Yahoo News

Rinse and repeat disease business model

Mastercard Foundation and Africa CDC announce $1.3 billion vaccine initiative

By Zamira Rahim and Stephanie Busari, CNN

(CNN)The Mastercard Foundation and the Africa Centres for Disease Control and Prevention (CDC) will deploy $1.3 billion over the next three years as part of a new initiative to acquire and deliver vaccines across the continent.

The Saving Lives and Livelihoods scheme aims to secure shots for more than 50 million people and help develop vaccine manufacturing in African countries, the organizations said in a press release Tuesday. The second wave of Covid-19 has hit Africa much harder than the first, according to analysis published in March in The Lancet medical journal.

"Ensuring equitable access and delivery of vaccines across Africa is urgent. This initiative is about valuing all lives and accelerating the economic recovery of the continent," said Reeta Roy, President and CEO of the Mastercard Foundation.

CNN

This underlies a serious flaw in diagnostic procedures
made in the AIDS 'crisis' in Africa -
they risk doing it again with COVID19...
anyone with a compromised immune system is vulnerable
to being labelled a carrier/infected

It may well be used to 'amplify' the true nature
of the pandemic for profit and political control

Scandemic Coup - redux

A group of philanthropic funds and investors led by the Soros Economic Development Fund (SEDF), with support from the Bill & Melinda Gates Foundation, is today announcing the launch of Global Access Health (GAH),

Mark Davis, chief executive officer of Mologic, welcomed the conclusion of the deal: “Mologic’s transition into a social enterprise is a deliberate, logical, and natural step for a company focused on delivering affordable diagnostics and biotechnology to places that have been left underserved by the relentless pursuit of profiteering. With the support of our shareholders, donors, and partners, we have come a long way; we believe we have the people and the skills required for the challenges and opportunities ahead. And we hope this unique transaction will be an example for others to follow.”

“Testing, or diagnostics, are vital for everyday public health needs, to enable doctors and medical professionals to provide patients with proper treatment as early as possible,” said Roxana Bonnell, a public health expert at the Open Society Foundations. “As we have seen during the COVID-19 pandemic, access to testing is absolutely essential when it comes to containing the spread of contagious disease—an issue that ultimately affects us all.”

As part of the transaction, GAH will integrate both Mologic and a sister nonprofit entity, Global Access Diagnostics (GAD), which was established by the founders of Mologic with support from SEDF, the U.K.’s Department of International Development, and others in April 2020. GAD is focused on low-cost manufacturing of diagnostic tests, and licenses Mologic’s technology in Africa and South Asia.

Open Society.Org

HIV Now Sets the Pace in the Bogus-vaxx Race

'HIV' and 'AIDS' are just as bogus as the 'novel coronavirus' and 'Covid.' Yet they're now setting the pace in the vaxx-development race.

Rosemary Frei, MSc . June 14, 2021

African Belt & Road initiative

Another mysterious death eh?

In the 12 months between 6 February 2020 and 6 February 2021, COVID-19 claimed the lives of at least 24 national ministers and heads of state, which is well in excess of the reported in-office death rate for such politicians in recent years. Seventeen of these deaths are from the African continent (and the count kept growing after 6 February 2021), putting the COVID-19 death rate at 1.33% among national ministers and heads of states—seven times above estimates of the world's average for a demographic profile of similar sex and age average for the same period.

While comorbidities such as obesity or diabetes cannot be ruled out as a cause of such African specificity, other hypotheses include the lower quality of healthcare and a halt in international medical transfers used by African elites as well as, later, the incidence of the so-called ‘South African’ variant (501Y.V2) of the virus.

The trend also invites careful reflection on the spread of COVID-19 in countries where data and testing are limited, especially among similar demographic profiles.

The deaths have an important symbolic value and have been associated with shifts in COVID-19 policies in some countries. They are also likely to result in some reconfiguration of the political space.

British medical Journal

HIV - DNA VAC trials 2015

DNA Vaccine that treats immunosuppressed

"directs human cells to produce a protein
that stimulates the body’s immune system
to generate protective antibodies"

DNAVAC 001

  • Research type

    Research Study

  • Full title

    DNAVAC001: A Phase 1 open-labelled trial to optimise DNA vaccination for antibody induction

  • IRAS ID

    161934

  • Contact name

    Robin Shattock

  • Contact email

    r.shattock@imperial.ac.uk

  • Sponsor organisation

    Joint Research Office

  • Eudract number

    2014-001997-33

  • Duration of Study in the UK

    1 years, 1 months, 1 days

2019 - Imperial scientists present vaccine revolution to world leaders at WEF in Davos

  • Research summary

    We are testing a vaccine, which consists of DNA that directs human cells to produce a protein that stimulates the body’s immune system to generate protective antibodies against the Human Immunodeficiency Virus (HIV).

    In this study we wish to work out the best conditions for using this DNA. Previous animal and human studies have shown that antibody responses to DNA vaccines can be influenced by the dose (amount of DNA), route of injection (into the muscle or skin), and use of electroporation (EP), which consists of mild millisecond electrical pulses at the site of injection.

    This greatly increases the amount of vaccine getting into cells, playing an important role in how well a vaccine works. Combining this vaccine with another type of DNA that promotes production of a natural human protein (recombinant IL-12) may further improve the way the vaccine works.

    Similar DNA vaccines have been tested in a number of clinical trials and found to be safe.

    In this study the vaccine will be administered by injection into the muscle (intramuscularly), skin (intradermally) or both (in thigh and/or upper arm) with and without DNA for recombinant interleukin 12, together with electroporation.

    We will invite healthy men and women to take part in this research. A total of 40-48 will be enrolled and each will receive four vaccinations over the course of 4-6 months. We will assess the effects of the vaccinations by recording any symptoms and by analysing blood samples over 6-9 months depending on vaccination schedule.

    The vaccine is already being studied in a small numbers of men and women by the IM route and to date has not caused any serious adverse events. However it has not previously been administered by electroporation with or without DNA for IL-12. Safety and efficacy will therefore be monitored extremely closely.

  • December 2020: Australia halts a vaccine, why?

    Australia on Friday canceled a roughly $750 million plan for a large order of a locally developed coronavirus vaccine after the inoculation produced false positive test results for H.I.V. in some volunteers participating in a trial study.

    Of the dozens of coronavirus vaccines being tested worldwide, the Australian one was the first to be abandoned. While its developers said the experimental vaccine had appeared to be safe and effective, the false positives risked undermining trust in the effort to vaccinate the public.

    NY Times

    The Mrna "Vaccines" are replacing human
    immune systems with a synthetic biology
    that you need to upgrade, via "Vaccine boosters"
    or face immune system compromise (V-AIDS)

    Bioweapon inside a Bioweapon?
    BBC video: HIV Fragment used in Vaccines

    J&J stop one jab Cov-19 starts RSV Vaccine production

    "...if you’re over age 65, have chronic heart or lung problems, or are immunocompromised because of another condition, you could have a higher risk of developing complications from RSV, such as bronchitis or pneumonia.”

    Johnson &Johnson

    UPDATE - The 2022 AIDS reboot:

    Coronavirus has an ‘HIV-like mutation’ which helps it to attack human cells, scientists claim (Feb. 27, 2020)

    Researchers Warn Some Covid-19 Vaccines Could Increase Risk Of HIV Infection (Oct. 20, 2020)

    Vaccine Acquired Immune Deficiency Syndrome (VAIDS): 'We should anticipate seeing this immune erosion more widely' (Dec. 6, 2021)

    Cases of vaccine-induced VAIDS on the rise due to mass covid vaccination (Dec. 10, 2021)

    Researchers Discover HIV Variant That's More Contagious, More Severe Circulating In The Netherlands

    A New HIV Vaccine Is In Phase One Trials. But Scientists Aren't Holding Their Breath Just Yet

    Free At-Home HIV Tests Available To The Public

    South African Scientists Will Study Link Between COVID Variants and Untreated HIV

    Newly Discovered HIV Variant Can Cause Patients To Develop AIDS Twice As Fast, Researchers Say

    Alberta Premier Jason Kenney apologizes for comparing unvaccinated people to AIDS patients

    Fauci Was Duplicitous on the AIDS Epidemic Too

    Video: Fauci in the 80s saying kids can get AIDS by being close to someone who has it

    Bio-Synthetic Genetic Software
    Operating on a Post-Human BioSystem

    much more @Spacestation Earth